The purine path to chemotherapy

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1989 English Publisher:Springer Science and Business Media LLCJournal:In Vitro Cellular & Developmental Biology, volume 25, pages 321-330 (issn: 0883-8364, eissn: 1475-2689,

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Authors: G B, Elion;

doi: 10.1007/bf02624593 , 10.1007/bf01119794 , 10.1126/science.2649979

pmid: 2649979

The purine path to chemotherapy

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Abstract

Antimetabolites of purine metabolism have found a use as anti-leukaemic, antiprotozoal and antiviral drugs, in immunosuppression and transplantation, and in gout and hyperuricemia. Their mechanisms of action are reviewed.

Related Organizations

Research Triangle Park Foundation
United States

Keywords

Drug Therapy, Purines, Animals, Humans

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