descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1980 English Publisher:Springer Science and Business Media LLCJournal:In Vitro, volume 16, pages 715-721 (issn: 0073-5655, eissn: 1475-2689,

Authors: E, Bey; I M, Spence; J J, Alexander; K, Robinson; R, Bernstein;

doi: 10.1007/bf02619201

pmid: 7419238

A human liposarcoma cell line

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Abstract

The properties of a new cell line derived from a human retroperitoneal liposarcoma are described. The cells do not grow at low cell concentrations and contain in their cytoplasm large numbers of droplets that stain with Oil Red O. No indication of the presence of endogenous virus particles could be found. The mean chromosome number per cell is 36, with several constant markers, the most conspicuous of which is a large submetacentric marker due to a translocation between chromosomes 4 and 11, which is present in every cell. The liposarcoma cells show an enhanced uptake of [14C]acetate compared to normal human fibroblasts.

Related Organizations

University of the Witwatersrand
South Africa
University of Natal
South Africa
National Institute of Virology
India
University of KwaZulu-Natal
South Africa

Keywords

Adult, Chromosome Aberrations, Liposarcoma, Acetates, Cell Line, Organoids, Cytopathogenic Effect, Viral, Karyotyping, Viruses, Cell Adhesion, Humans, Female, Cell Division

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