Significance of examination of prostate-specific antigen and prostate-specific antigen density in patients with prostatic hyperplasia and prostate cancer

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1997 English Publisher:Springer Science and Business Media LLCJournal:International Urology and Nephrology, volume 29, pages 449-455 (issn: 0301-1623, eissn: 1573-2584,

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Authors: I, Romics; D, Frang; I, Bodrogi;

doi: 10.1007/bf02551112

pmid: 9406003

Significance of examination of prostate-specific antigen and prostate-specific antigen density in patients with prostatic hyperplasia and prostate cancer

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Abstract

Authors investigated PSA concentration and preoperative prostate volume in 113 histologically proved BPH and 31 prostatic cancer patients. PSA concentration was measured with the Hybritech kit, the prostate volume by ultrasound with the help of an ellipse and calculated by computer. There was no correlation between the age of patients and volume of the prostate, whereas a correlation was proved between marker concentration and prostate volume (p < 0.0001). The difference obtained by the correlation of the prostate volume and the PSA concentration ratio between the BPH and 31 tumorous patients (PSA density) was highly significant (0.143 vs. 0.699, p < 0.001). The use of PSAD further improves the diagnostic value of PSA.

Related Organizations

Semmelweis University
Hungary
National Institute of Oncology
Hungary

Keywords

Aged, 80 and over, Male, Age Factors, Prostate, Prostatic Hyperplasia, Prostatic Neoplasms, Organ Size, Middle Aged, Prostate-Specific Antigen, Humans, Aged, Ultrasonography

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