An investigation was carried out on the therapeutic value of chlorhexidine (I.C.I.). We are of the opinion that this substance, which has very few toxic side-effects, may prove to be of great importance as a general disinfectant in surgical practice, of prophylactic value in paediatrics, in urogical practice, in the treatment of burns, and generally to prevent cross infection. Further, it was established that chlorhexidine possesses fungistatic and fungicidal action.