Observations on the lyophilization ofBrucella abortus, strain 19

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1956 English Publisher:Springer Science and Business Media LLCJournal:Antonie van Leeuwenhoek, volume 22, pages 193-204 (issn: 0003-6072, eissn: 1572-9699,

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Authors: A F, VAN DER SCHEER;

doi: 10.1007/bf02538327

pmid: 13340706

Observations on the lyophilization ofBrucella abortus, strain 19

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Abstract

For the production of lyophilizedBrucella abortus Str. 19 vaccine a suspending medium containing 2% tryptose, 0.5% neutralised ascorbic acid and 0.75% thiourea was developed. In 100 separate batches of vaccine dried in this medium the survival rate was determined after primary drying and after secondary drying and vacuum-sealing of the ampoules.

Related Organizations

Statens Serum Institut
Denmark

Keywords

Survival Rate, Freeze Drying, Brucella abortus

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