Stability of prostaglandin E compounds in solution

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1973 English Publisher:WileyJournal:Lipids, volume 8, pages 592-594 (issn: 0024-4201, eissn: 1558-9307,

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Authors: K C, Srivastava; J, Clausen;

doi: 10.1007/bf02532717

pmid: 4750538

Stability of prostaglandin E compounds in solution

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Abstract

AbstractIn the present paper the stability of prostaglandins E1, E2, and E3 has been studied in two types of solvents: (a) solvents in which they can be used in clinical trials and (b) solvents which are commonly used for their isolation from biological systems. The solvents used in the first type were ethanol, saline, and water while those in the second type were chloroform and ethylacetate. In addition to this the effect of light on stability of these prostaglandins in chloroform also has been studied.

Keywords

Solutions, Time Factors, Drug Stability, Ethanol, Light, Prostaglandins, Esters, Chloroform, Chromatography, Thin Layer, Acetates

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