Electrode placement on one hand and one foot remains as the generally accepted method for the measurement of the total body bioelectrical impedance, although these anatomical locations have often been employed without regards as to their suitability in various populations. For measurements of BI in a relatively small number of infants, it was suggested that these anatomical landmarks for electrode placements are satisfactory, provided that the signal and sensor electrodes are separated by a distance of 2 or 2.5 cm to avoid artifactual increases in body impedance. Although specific to electrode displacement on the upper limb, the adjustment factors noted herein should permit more precise determinations of total body BI in the neonatal population.