Serum antioxidant enzyme activity in Parkinson's disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1992 English Publisher:Springer Science and Business Media LLCJournal:Molecular and Cellular Biochemistry, volume 110, pages 165-168 (issn: 0300-8177, eissn: 1573-4919,

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Authors: J, Kalra; A H, Rajput; S V, Mantha; K, Prasad;

doi: 10.1007/bf02454194

pmid: 1584206

Serum antioxidant enzyme activity in Parkinson's disease

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Abstract

The activities of superoxide dismutase (SOD; EC 1.15.1.1) and glutathione peroxidase (GSHPx; EC 1.11.1.9), the enzymes that metabolize the superoxide anion and hydrogen peroxide, respectively, were measured in serum from healthy subjects and patients with Parkinson's disease (PD). The activities of SOD and GSHPx in patients with PD were higher than those in normal healthy individuals. These results suggest that the increased activities of these enzymes could be due to oxidative stress in the initial stages of this disease.

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Keywords

Male, Glutathione Peroxidase, Superoxide Dismutase, Humans, Female, Parkinson Disease, Middle Aged, Antioxidants, Aged

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