In vivo efficiency of Semax in global cerebral ischemia

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1999 English Publisher:Springer Science and Business Media LLCJournal:Bulletin of Experimental Biology and Medicine, volume 128, pages 806-807 (issn: 0007-4888, eissn: 1573-8221,

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Authors: E. V. Yakovleva; V. S. Kuzenkov; V. N. Fedorov; V. I. Skvortsova; V. B. Koshelev; E. I. Gusev; I. P. Ashmarin;

doi: 10.1007/bf02433821

In vivo efficiency of Semax in global cerebral ischemia

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Abstract

The efficiency of neuropeptide preparation Semax was studied on an animal model of global cerebral ischemia caused by irreversible bilateral occlusion of the common carotid arteries. Semax significantly alleviated neurological deficit and slightly improved postischemic survival. These effects can be attributed to the antihypoxic and neurotrophic effects of the preparation.

Related Organizations

Lomonosov Moscow State University
Russian Federation
Pirogov Russian National Research Medical University
Russian Federation

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