Antibody engineering, a strategy for the development of monoclonal antibodies
Copyright policy )Antibody engineering, a strategy for the development of monoclonal antibodies
Antibody engineering is the selection process enabling the isolation of hybridoma clones, each of which produces an antibody with predefined qualities. The state of the art of hybridoma technology is reviewed with emphasis on the results obtained by antibody engineering in our laboratories for the development of monoclonal antibodies for specific use in diagnostic tests. The perspective for in vitro monoclonal antibody production as well as the application of monoclonal antibodies for diagnostic reagents, industrial purification and therapeutic use are indicated.
- Organon International Netherlands
B-Lymphocytes, Herpesvirus 4, Human, Hybridomas, Antibodies, Monoclonal, DNA, Neoplasm, Cell Transformation, Viral, Cell Line, Clone Cells, Rats, Cell Fusion, Mice, Cell Transformation, Neoplastic, Immunogenetics, Animals, Humans, Immunization, Rabbits, Multiple Myeloma
B-Lymphocytes, Herpesvirus 4, Human, Hybridomas, Antibodies, Monoclonal, DNA, Neoplasm, Cell Transformation, Viral, Cell Line, Clone Cells, Rats, Cell Fusion, Mice, Cell Transformation, Neoplastic, Immunogenetics, Animals, Humans, Immunization, Rabbits, Multiple Myeloma
citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).16 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!