Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1975 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 31, pages 1,212-1,213 (issn: 0014-4754, eissn: 1420-9071,

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Authors: E L, Shaver;

doi: 10.1007/bf02326800

pmid: 1204746

Pentobarbital sodium and chromosome abnormalities in rabbit blastocysts

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Abstract

Female rabbits were injected with pentobarbital sodium at 1/4 h or 6 h post coitum. A slight delay in oocyte maturation was evident in animals killed at 17 h pc, however, zygote development appeared normal by 24 h pc. At 6 days pc, a greater frequency of chromosomally abnormal blastocysts was found in animals injected with pentobarbital than in control rabbits.

Related Organizations

Health Sciences Centre
Canada
Western University
Canada

Keywords

Chromosome Aberrations, Ovulation, Chromosome Disorders, Gestational Age, Blastocyst, Pregnancy, Fertilization, Animals, Female, Rabbits, Pentobarbital

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