1. Seven cases of carcinoma originating in the jejunum have been presented. 2. The clinical features of pain, vomiting, and anemia are late in appearance and are not diagnostic in themselves. 3. “Routine” gastrointestinal x-ray study may frequently fail to disclose a small intestinal lesion. The clinician must more often suspect the small bowel as a source of trouble and request special radiographic study. 4. Resection with attempt to cure is the therapeutic method of choice. The possibility of greater salvage with “second look” operation is suggested. 5. The prognosis is poor. The 5-year cure rate is 20 to 25 per cent, and average survival is less than 3 years. 6. A plea is registered for the steps leading to earlier diagnosis of this condition.