CUG codons inCandida spp.

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1996 English Publisher:Springer Science and Business Media LLCJournal:Journal of Molecular Evolution, volume 42, pages 321-322 (issn: 0022-2844, eissn: 1432-1432,

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Authors: T H, Jukes; S, Osawa;

doi: 10.1007/bf02198859

pmid: 8919884

CUG codons inCandida spp.

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Abstract

Codon CUG is used for serine instead of for leucine, its usual assignment, in several yeasts of the genus Candida. We propose a series of steps for the reassignment, including disappearance of leucine CUG and its anticodon CAG, formation of a new serine tRNA, with anticodon CAG, from a duplication of the gene for serine tRNA (IGA), and then production of CUG codons by mutation at sites that are mostly "nonessential."

Related Organizations

University of California, Berkeley
United States
Space Sciences Laboratory
United States

Keywords

Evolution, Molecular, Base Sequence, Models, Genetic, Leucine, Anticodon, Serine, RNA, Fungal, Codon, DNA, Fungal, Candida

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