An extraction method for the determination of the Rose Bengal content in the preparations of Rose Bengal labelled with131I

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1985 English Publisher:Springer Science and Business Media LLCJournal:Journal of Radioanalytical and Nuclear Chemistry Letters, volume 93, pages 199-205 (issn: 0236-5731, eissn: 1588-2780,

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Authors: J. Lengyel; J. Krtil; J. Večerník;

doi: 10.1007/bf02170236

An extraction method for the determination of the Rose Bengal content in the preparations of Rose Bengal labelled with131I

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Abstract

The paper describes an extraction radiometric method for the determination of Rose Bengal content in the radiopharmaceutical preparations of Rose Bengal labelled with131I. Two methods have been studied. The first one is based on the addition of an excess and substoichiometric amounts of Septonex /carbetoxypentadecyltrimethylammonium bromide/ to the sample of Rose Bengal-131I and on the activity measuring of the chloroform extracts. The second method is based on the extraction of Rose Bengal-131I with substoichiometric amount of Septonex from the sample of Rose Bengal-131I and the sample of Rose Bengal-131I diluted with a known amount of an inactive Rose Bengal preparation.

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