Enhancement of fibrinolysis and thrombolysis by polysorbate 80 (Tween 80®)

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1967 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 23, pages 261-262 (issn: 0014-4754, eissn: 1420-9071,

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Authors: H C, Kwaan; P, Brakman; T, Astrup;

doi: 10.1007/bf02135671

pmid: 6055924

Enhancement of fibrinolysis and thrombolysis by polysorbate 80 (Tween 80®)

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Abstract

Polysorbate 80 (Tween 80®), eine polyhydroxyle, nicht-ionisierbare, oberflachenaktive Substanz, vermindert die Adsorption von Urokinase an Glas, erhoht deren fibrinolytische Aktivitat in vitro und steigert ihre thrombolytische Wirkung in experimentell hervorgerufenen Thrombosen im Kaninchen.

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Premier Clinical Research Institute
United States

Keywords

Fibrinolysis, Fatty Acids, Phosphotransferases, Thrombosis, In Vitro Techniques, Surface-Active Agents, Fish Oils, Animals, Female, Adsorption, Glass, Rabbits

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