Envelope and nucleocapsid antigens of Cytomegalovirus (CMV)

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1975 English Publisher:Springer Science and Business Media LLCJournal:Medical Microbiology and Immunology, volume 161, pages 155-162 (issn: 0300-8584, eissn: 1432-1831,

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Authors: H, Schmitz; H W, Doerr; M, Obrig;

doi: 10.1007/bf02121005

pmid: 171550

Envelope and nucleocapsid antigens of Cytomegalovirus (CMV)

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Abstract

A method for the purification and concentration of Cytomegalovirus nucleocapsids and particles complete with envelope is described. Antibody to either nucleocapsid or envelope antigens can be detected in human sera. In patients with CMV disease the antibodies to the envelope antigen could not be detected before the 3rd week after the beginning of disease whereas antibodies to the nucleocapsid were detected earlier.

Related Organizations

University of Freiburg
Germany

Keywords

Time Factors, Cytomegalovirus, Fibroblasts, Antibodies, Viral, Viral Proteins, Capsid, Cytomegalovirus Infections, Centrifugation, Density Gradient, Humans, Antigens, Viral

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