Functional domains of the gonadotropin-releasing hormone receptor
Copyright policy )Functional domains of the gonadotropin-releasing hormone receptor
1. The cloning of the mammalian gonadotropin-releasing hormone receptor sets the stage for rapid progress in understanding the structure of the receptor, its interaction with ligand, and its mechanisms of activation. 2. The receptor is a 327 to 328-amino acid seven-transmembrane domain G protein-coupled receptor. 3. Recent site-direct mutagenesis studies have provided considerable insight into glycosylation of the receptor, the arrangement of the helices, and the ligand binding domains.
- Icahn School of Medicine at Mount Sinai United States
- University of Cape Town South Africa
Mammals, Sheep, Sequence Homology, Amino Acid, Protein Conformation, Molecular Sequence Data, Recombinant Proteins, Rats, Mice, Animals, Humans, Cattle, Amino Acid Sequence, Cloning, Molecular, Receptors, LHRH
Mammals, Sheep, Sequence Homology, Amino Acid, Protein Conformation, Molecular Sequence Data, Recombinant Proteins, Rats, Mice, Animals, Humans, Cattle, Amino Acid Sequence, Cloning, Molecular, Receptors, LHRH
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