
doi: 10.1007/bf02065209
pmid: 5721059
The special features in the evolution of collagen are the differentiation of the chains and a physiological improvement of the thermal stability of the secondary structure. The small number of mutations restricted by the helical structure facilitates the correlations between the chemical differences and the evolutionary schemes. The relations of the structure with the tensile strength and the bone formation as also the significance of the associated non-collagen substances remain to be evaluated.
Protein Denaturation, Species Specificity, Mutation, Temperature, Humans, Collagen, Amino Acids, Biological Evolution
Protein Denaturation, Species Specificity, Mutation, Temperature, Humans, Collagen, Amino Acids, Biological Evolution
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