descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Dec 1970 English Publisher:Springer Science and Business Media LLCJournal:Zeitschrift für die gesamte experimentelle Medizin einschließlich experimentelle Chirurgie, volume 153, pages 237-245 (issn: 0372-8722, eissn: 1433-8580,

Authors: R Sanwald; E Ritz;

doi: 10.1007/bf02048757

pmid: 5526833

Glucuronic acid cycle in arterial tissue

- Summary
- Subjects
- Metrics

Abstract

The presence of all enzymatic steps of the glucuronic acid pathway could be demonstrated in arteries of various species.14C-D-glucose was converted into14C-D-glucuronic acid; 6-14C-D-glucuronic acid was decarboxylated to14CO2 and U-14C-D-glucuronic acid was transformed into14C-xylitol. NADP-L-xylulose oxidoreductase (E.C. 1.1.1.10) could be shown in tissue homogenate. Myoinositol was not converted into glucuronic acid in arteries. The rate of decarboxylation of glucuronic acid in various species was identical irrespective of the presence of ascorbic acid synthesis. The rate of decarboxylation of 6-14C-D-glucuronic acid and the rate of transformation of U-14C-D-glucose into14C-D-glucuronic acid was not elevated in alloxandiabetic animals and the activity of L-xylulose-oxidoreductase was unchanged in animals with experimental diabetes.

Keywords

Male, Carbon Isotopes, Chromatography, Paper, Guinea Pigs, Glucuronates, Arteries, Ascorbic Acid, Carbon Dioxide, Decarboxylation, Diabetes Mellitus, Experimental, Femoral Artery, Alcohol Oxidoreductases, Glucose, Adipose Tissue, Diabetes Mellitus, Animals, Humans, Oxidoreductases, Aorta, Diabetic Angiopathies

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	2
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average