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Viral antibodies in multiple sclerosis

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jun 1982Publisher:Springer Science and Business Media LLCJournal:The Italian Journal of Neurological Sciences, volume 3, pages 115-118 (issn: 0392-0461, eissn: 1126-5442,

Authors: S. Barbesti; Pasquale Ferrante; M. Fasan; D. Caputo;

doi: 10.1007/bf02043942

pmid: 6288620

pmc: PMC7088060

Viral antibodies in multiple sclerosis

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Abstract

The sera of 176 MS patients and of 150 healthy adult controls were assayed for antibodies against mumps, rubella, Sendai and herpes simplex viruses, a higher prevalence of measles c.f.a. having already been demonstrated in the MS patients. The CSF of 48 of the MS patients were subjected to the same tests. The patients differed from the controls in a higher prevalence of h.i.a. to mumps and of c.f.a. to herpes simplex. For the latter, but not for the former, the prevalence was statistically higher only in patients treated with immunosuppressants. To date measles seems to be the most seriously incriminated virus in the etiopathogenesis of MS, mumps ranking second.

Related Organizations

University of Milan
Italy

Keywords

Multiple Sclerosis, Mumps virus, Humans, Simplexvirus, Original Articles, Antibodies, Viral, Rubella virus, Parainfluenza Virus 1, Human

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