
doi: 10.1007/bf02034673
pmid: 32067
A new procedure utilizing dried blood spots was developed for detecting glutathione peroxidase deficiency. Samples from a known patient with a partial defect and from rats with an induced deficiency were distinguished from respective control groups by their longer defluorescence endpoints. Samples from 100 patients with anemia and 2 phenyl-ketonuric infants on low-protein diets contained glutathione peroxidase activity similar to that in 82 controls, when screened for the enzyme defect by the new procedure.
Adult, Glutathione Peroxidase, Infant, Newborn, Infant, Anemia, Middle Aged, Fluorescence, Rats, Selenium, Peroxidases, Phenylketonurias, Methods, Animals, Humans, Mass Screening, Child, Metabolism, Inborn Errors, NADP
Adult, Glutathione Peroxidase, Infant, Newborn, Infant, Anemia, Middle Aged, Fluorescence, Rats, Selenium, Peroxidases, Phenylketonurias, Methods, Animals, Humans, Mass Screening, Child, Metabolism, Inborn Errors, NADP
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