
Beta-aminopropionitrile (BAPN) is an inhibitor of pig plasma benzylamine oxidase. BAPN is oxidized by benzylamine oxidase. Inhibition develops in a time-dependent fashion upon incubation of BAPN with the enzyme in the absence of substrate. The product of oxidation of BAPN by benzylamine oxidase, cyanacetaldehyde, was identified and prepared by synthesis. It is an irreversible inhibitor of the enzyme.
Monoamine Oxidase Inhibitors, blood and hemopoietic system; drug efficacy; enzyme blood level; enzyme inhibition, Swine, Aminopropionitrile, Animals, Hydrogen Peroxide, Benzylamine Oxidase, Monoamine Oxidase, Oxidation-Reduction
Monoamine Oxidase Inhibitors, blood and hemopoietic system; drug efficacy; enzyme blood level; enzyme inhibition, Swine, Aminopropionitrile, Animals, Hydrogen Peroxide, Benzylamine Oxidase, Monoamine Oxidase, Oxidation-Reduction
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