<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://www.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Naloxone and intestinal motility

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 1978Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 34, pages 1,310-1,311 (issn: 0014-4754, eissn: 1420-9071,

Authors: A. Palekar; A. Adamovics; R. A. Howd;

doi: 10.1007/bf01981437

pmid: 216571

Naloxone and intestinal motility

- Summary
- Subjects
- Metrics

Abstract

It was supposed that the inhibition of intestinal peristalsis seen in animals and humans after abdominal surgery might be related to the release of endorphins, endogenous opiate receptor agonists, caused by the surgical stress and pain. However, naloxone, a potent morphine and endorphin antagonist, failed to block this peristaltic inhibition in rats, which leaves the mechanism of this inhibition, and thus the function of intestinal endorphins, still very much in doubt.

Related Organizations

SRI International
United States
Direction de la Recherche Fondamentale
France

Keywords

Male, Naloxone, Stress, Physiological, Receptors, Opioid, Animals, Endorphins, Gastrointestinal Motility, Rats

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	22
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average