Leucotrienes, SRS-A and the vascular manifestations of PCA
Copyright policy )Leucotrienes, SRS-A and the vascular manifestations of PCA
In order to study possible mediators of the vascular manifestations of passive cutaneous anaphylaxis (PCA), several arachidonic acid metabolites were injected into guinea-pig skin. SRS-A, LTB4, LTC and LTD increased vascular permeability, responses to LTs being enhanced by PGE2. Mepyramine inhibited responses to histamine, but not those to SRS-A and LTs; the latter were inhibited by the SRS-A antagonist FPL-55712. Both mepyramine and FPL-55712 exert limited inhibitory effects on vascular permeability during PCA. Leukotrienes may contribute towards vascular permeability during PCA.
Arachidonic Acid, Prostaglandins E, Guinea Pigs, Passive Cutaneous Anaphylaxis, Arachidonic Acids, Blood Proteins, In Vitro Techniques, Dinoprostone, Animals, Blood Vessels, SRS-A, Lung, Autacoids, Histamine
Arachidonic Acid, Prostaglandins E, Guinea Pigs, Passive Cutaneous Anaphylaxis, Arachidonic Acids, Blood Proteins, In Vitro Techniques, Dinoprostone, Animals, Blood Vessels, SRS-A, Lung, Autacoids, Histamine
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).19 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!