Regulation of acute phase reaction in rat adjuvant arthritis

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1986 English Publisher:Springer Science and Business Media LLCJournal:Agents and Actions, volume 19, pages 335-336 (issn: 0065-4299, eissn: 1420-908X,

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Authors: R, Hirschelmann; R, Schade;

doi: 10.1007/bf01971243

pmid: 2435117

Regulation of acute phase reaction in rat adjuvant arthritis

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Abstract

Local low dose injection of actinomycin D into the inflamed tissue as well as administration of a glucocorticoid antagonist is apparently suitable for investigating the regulation of acute phase reactionin vivo. The acute phase protein synthesis in the liver is apparently triggered by several factors derived from the inflamed tissue, not only by one substance (IL-1).

Related Organizations

Martin Luther University Halle-Wittenberg
Germany
Humboldt-Universität zu Berlin
Germany

Keywords

Inflammation, Arthritis, Rats, Inbred Strains, Arthritis, Experimental, Rats, Dactinomycin, Animals, Female, Acute-Phase Reaction, Acute-Phase Proteins

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