
doi: 10.1007/bf01963957
pmid: 499398
Synephrine (SP) was found to be a substrate for monoamine oxidase (MAO) in rat brain mitochondria, showing the Km and Vmax values of 250 microM and 32.6 nmoles/mg of protein/30 min respectively. The inhibition studies showed that the SP oxidation was carried out by both type A and type B MAO and a major part of the activity was due to type A MAO.
Male, Clorgyline, Dose-Response Relationship, Drug, Synephrine, Brain, Mitochondria, Rats, Kinetics, Selegiline, Animals, Monoamine Oxidase
Male, Clorgyline, Dose-Response Relationship, Drug, Synephrine, Brain, Mitochondria, Rats, Kinetics, Selegiline, Animals, Monoamine Oxidase
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