Effects of mitogens on ADCC activity and Fc receptor bearing cells

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1983 United States English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 39, pages 34-39 (issn: 0014-4754, eissn: 1420-9071,

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Authors: Hugin, A; Matter, A;

doi: 10.1007/bf01960618

pmid: 6337863

Effects of mitogens on ADCC activity and Fc receptor bearing cells

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Abstract

Murine spleen cells, when activated by various mitogens (Con A, PHA, LPS, BCG) or Con-A conditioned medium show altered behavior as effector cells of antibody-mediated cell cytotoxicity (ADCC) which does not correlate with the expression of Fc-receptors (FcR) at the effector cell surface.

Country

United States

Related Organizations

Jackson Laboratory
United States
Roche (Switzerland)
Switzerland

Keywords

Serology: Antigen, Lipopolysaccharides, C3H/HE, Mice, Inbred C3H, Rosette Formation, Antibody-Dependent Cell Cytotoxicity, Receptors, Fc, C3H, Mycobacterium bovis, Organs:, Mice, Strains: CBA, Concanavalin A, Mice, Inbred CBA, Animals, Lymphocytes, Mitogens, Phytohemagglutinins, Cells, Cultured, Spleen

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