Cytotoxicity of ethyl methanesulfonate in mice spermatogonia
Copyright policy )Cytotoxicity of ethyl methanesulfonate in mice spermatogonia
Enumeration of different types of spermatogonia, following a single i.p. administration of different doses of ethyl methanesulfonate in mice, showed a survival of A1-A4 and in spermatogonia is markedly reduced due to cell killing while the remaining types of spermatogonia were affected marginally. The cell killing effect was dose-dependent, and replenishment of these cells was observed by the end of one cycle of the seminiferous epithelium comprising of 8.5 days.
Male, Mesylates, Time Factors, Dose-Response Relationship, Drug, Cell Survival, Spermatozoa, Spermatogonia, Mice, Ethyl Methanesulfonate, Animals
Male, Mesylates, Time Factors, Dose-Response Relationship, Drug, Cell Survival, Spermatozoa, Spermatogonia, Mice, Ethyl Methanesulfonate, Animals
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