Mastoparan induces hypothermia in mice
Copyright policy )Mastoparan induces hypothermia in mice
The polypeptide mastoparan, isolated from the venom of the Oriental Hornet, Vespa orientalis, induces hypothermia in white mice 15 minutes after its intraperitoneal injection. The hypothermic effect is induced by mastoparan obtained from different hornet and wasp venoms. The normal murine core temperature is lowered by mastoparan from 38 degrees C to as far as 33 degrees C. This lowering lasts for one hour and is reversible.
- Tel Aviv University Israel
Male, Mice, Mice, Inbred ICR, Molecular Sequence Data, Wasps, Animals, Intercellular Signaling Peptides and Proteins, Electrophoresis, Polyacrylamide Gel, Wasp Venoms, Amino Acid Sequence, Hypothermia, Peptides
Male, Mice, Mice, Inbred ICR, Molecular Sequence Data, Wasps, Animals, Intercellular Signaling Peptides and Proteins, Electrophoresis, Polyacrylamide Gel, Wasp Venoms, Amino Acid Sequence, Hypothermia, Peptides
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