The generation and identification of the hemolysin of Trypanosoma congolense

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1977 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 33, pages 901-902 (issn: 0014-4754, eissn: 1420-9071,

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Authors: I R, Tizard; W L, Holmes; D A, York; A, Mellors;

doi: 10.1007/bf01951271

pmid: 891767

The generation and identification of the hemolysin of Trypanosoma congolense

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Abstract

The hemolytic activity of Trypanosoma congolense appears to be due to the presence of free fatty acids generated by the action of phospholipase A on endogenous phosphatidyl choline. Some lysolecithin also contributes to the lytic activity. Trypanosoma lewisi, being devoid of phospholipase A, does not generate free fatty acids and is therefore non-hemolytic.

Related Organizations

University of Guelph
Canada

Keywords

Trypanosoma, Erythrocytes, Sheep, Lysophosphatidylcholines, Lipase, Fatty Acids, Nonesterified, Hemolysis, Hemolysin Proteins, Phospholipases, Animals

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