Rifampicin and cysteamine protect against the mushroom toxin phalloidin

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1974 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 30, pages 1,310-1,312 (issn: 0014-4754, eissn: 1420-9071,

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Authors: G L, Floersheim;

doi: 10.1007/bf01945202

pmid: 4373285

Rifampicin and cysteamine protect against the mushroom toxin phalloidin

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Abstract

Der Schutzefekt von Rifampicin gegen eine Letaldosis des Pilzgiftes Phalloidin wurde bestatigt und weiter charakterisiert. Auch Cysteamin erwies sich als wirksam. Keinen Schutz gegen Phalloidin boten Stoffe, welche das Pilzgift α-Amanitin antagonisieren. Die hepatotoxische Wirkungskomponente der meisten Phalloidin-Antagonisten wird erortert.

Keywords

Reserpine, Cysteamine, Cytochrome c Group, Penicillin G, Mushroom Poisoning, Mycotoxins, Guanidines, Erythromycin, Rats, Lethal Dose 50, Mice, Liver, Phenylbutazone, Animals, Female, Antitoxins, Rifampin, Chlortetracycline

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