Prokaryotic genetic code

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1990 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 46, pages 1,097-1,106 (issn: 0014-4754, eissn: 1420-9071,

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Authors: S, Osawa; A, Muto; T, Ohama; Y, Andachi; R, Tanaka; F, Yamao;

doi: 10.1007/bf01936919

pmid: 2253708

Prokaryotic genetic code

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Abstract

The prokaryotic genetic code has been influenced by directional mutation pressure (GC/AT pressure) that has been exerted on the entire genome. This pressure affects the synonymous codon choice, the amino acid composition of proteins and tRNA anticodons. Unassigned codons would have been produced in bacteria with extremely high GC or AT genomes by deleting certain codons and the corresponding tRNAs. A high AT pressure together with genomic economization led to a change in assignment of the UGA codon, from stop to tryptophan, in Mycoplasma.

Related Organizations

Nagoya University
Japan

Keywords

Base Composition, Bacteria, Base Sequence, Molecular Sequence Data, Biological Evolution, Prokaryotic Cells, RNA, Transfer, Species Specificity, Genetic Code, Anticodon, Codon

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