Mammalian spot test with moxnidazole, a 5-nitroimidazole

descriptionPublicationkeyboard_double_arrow_right Article 01 Apr 1978 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 34, pages 500-501 (issn: 0014-4754, eissn: 1420-9071,

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Authors: R, Lang;

doi: 10.1007/bf01935953

pmid: 565299

Mammalian spot test with moxnidazole, a 5-nitroimidazole

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Abstract

Moxnidazole [3-(5-nitrol-1-methyl-2-imidazolyl)-methyleneamino-5-morpholinomethyl-2-oxazolidinone, HCl], known to be mutagenic in microbial tests and Drosophila, induced genetic alterations in somatic cells of mice. Ethyl methanesulfonate (EMS) served as positive control.

Related Organizations

Schering AG
Germany

Keywords

Genotype, Pigmentation, Embryo, Mammalian, Mice, Nitroimidazoles, Pregnancy, Animals, Female, Oxazoles, Oxazolidinones, Mutagens

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