Synthesis of ochratoxins TA and TC, analogs of ochratoxins A and C

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 1974 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 30, pages 174-175 (issn: 0014-4754, eissn: 1420-9071,

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Authors: R D, Wei; F S, Chu;

doi: 10.1007/bf01927717

pmid: 4814604

Synthesis of ochratoxins TA and TC, analogs of ochratoxins A and C

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Abstract

Zwei Ochratoxinanaloge, Ochratoxin TA (OTA) und TC (OTC) wurden aus Ochratoxin-α chemisch synthetisiert indem Phenylalanin und sein Athylester im Molekul durch Tyrosin und Tyrosinathylester substituiert wurden. Der Huhnerembryonentest ergab, dass OTC etwas toxischer und OTA etwas weniger toxisch ist als Ochratoxin A (OA).

Related Organizations

University of Wisconsin–Oshkosh
United States
University of Wisconsin–Madison
United States

Keywords

Aspergillus, Animals, Chick Embryo, Chromatography, Thin Layer, Ochratoxins, Mass Spectrometry

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