In vitro cytostatic effect of adenine-arabinoside (Ara-A) and cytosine-arabinoside (Ara-C)

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1978 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 34, pages 1,219-1,220 (issn: 0014-4754, eissn: 1420-9071,

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Authors: C, Nissen; J, Henauer; B, Speck;

doi: 10.1007/bf01922968

pmid: 720532

In vitro cytostatic effect of adenine-arabinoside (Ara-A) and cytosine-arabinoside (Ara-C)

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Abstract

Adenine-arabinoside, a new antiviral drug with questionable bone marrow toxicity, inhibits colony formation by myeloid precursor cells in vitro. Compared to cytosine-arabinoside this cytotoxicity is roughly one third.

Keywords

Dose-Response Relationship, Drug, Bone Marrow, Cell Survival, Cytarabine, Humans, Cell Division, Cells, Cultured, Vidarabine

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