descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1977 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 33, pages 1,474-1,475 (issn: 0014-4754, eissn: 1420-9071,

Authors: M C Laury; René Portet;

doi: 10.1007/bf01918816

pmid: 200459

Corticotropin and nonshivering thermogenesis

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Abstract

Chronic treatment with corticotropin led to reduced calorigenic effect of norepinephrine in cold acclimatized rats, but potentiated its effect in controls. This inhibitory effect was not due to the observed decrease in corticosterone plasma level, as it was shown by metopirone administration. It is concluded that corticotropin could have a competitive action on receptor sites mediating the calorigenic effect of norepinephrine in nonshivering thermogenesis.

Related Organizations

École Pratique des Hautes Études
France

Keywords

Norepinephrine, Adrenocorticotropic Hormone, Acclimatization, Shivering, Animals, Metyrapone, Body Temperature Regulation, Rats

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