Anti-phalloidine and anti-α-amanitine action of silybin in comparison with compounds similar to structural parts of silybin

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 1978 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 34, pages 1,051-1,052 (issn: 0014-4754, eissn: 1420-9071,

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Authors: W, Trost; G, Halbach;

doi: 10.1007/bf01915341

pmid: 700023

Anti-phalloidine and anti-α-amanitine action of silybin in comparison with compounds similar to structural parts of silybin

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Abstract

Silybin significantly antagonises the lethal poisoning of mice with alpha-amanitine or phalloidine. In the same test, taxifolin, coniferyl alcohol, fisetin and (+)-catechin were not effective.

Keywords

Flavonoids, Male, Amanitins, Flavonols, Phalloidine, Catechin, Mice, Structure-Activity Relationship, Phenols, Cinnamates, Alcohols, Animals, Female, Quercetin, Oligopeptides, Silymarin

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