Inactivation of tissue-specific inhibitors by a carcinogen (diethylnitrosamine)

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1969 English Publisher:Springer Science and Business Media LLCJournal:Experientia, volume 25, pages 68-69 (issn: 0014-4754, eissn: 1420-9071,

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Authors: M, Volm; V, Kinzel; U, Mohr; R, Süss;

doi: 10.1007/bf01903901

pmid: 5766588

Inactivation of tissue-specific inhibitors by a carcinogen (diethylnitrosamine)

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Abstract

Der Einbau von Thymidin in Leberexplantate wird durch losliche Leberproteine gehemmt. Diese Hemmung ist aufgehoben, wenn die Proteine aus Lebern karzinogenbehandelter Tiere prapariert wurden. Dieser Effekt ist organspezifisch.

Related Organizations

German Cancer Research Center
Germany
Helmholtz Association of German Research Centres
Germany

Keywords

Nitrosamines, Proteins, Antineoplastic Agents, DNA, Tritium, Rats, Animals, Newborn, Liver, Organ Specificity, Culture Techniques, Depression, Chemical, Carcinogens, Animals, Protein Binding, Thymidine

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