Cytokines and legionellosis

descriptionPublicationkeyboard_double_arrow_right Article , Part of book or chapter of book 01 Jan 1994 English Publisher:Springer Science and Business Media LLCJournal:Biotherapy, volume 7, pages 179-186 (issn: 0921-299X, eissn: 1573-8280,

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Authors: T F, Byrd;

doi: 10.1007/bf01878484 , 10.1007/978-94-011-0233-9_5

pmid: 7865349

Cytokines and legionellosis

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Abstract

Recent studies have led to an enhanced understanding of the role of cell-mediated immunity and cytokines in Legionnaires' disease. In particular, the effect of interferon gamma on human mononuclear phagocyte iron metabolism and the role of iron availability of Legionella pneumophila intracellular multiplication in human monocytes has been elucidated. With this knowledge it is now possible to develop treatment strategies for Legionnaires' disease using interferon gamma and/or agents affecting human mononuclear phagocyte iron metabolism.

Related Organizations

West Los Angeles College
United States

Keywords

Immunity, Cellular, Animals, Cytokines, Humans, Legionnaires' Disease, Legionella pneumophila

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