Hyperactivation of fibroplasia by the transferable sulphur in wound healing

descriptionPublicationkeyboard_double_arrow_right Article 01 Sep 1974 English Publisher:Springer Science and Business Media LLCJournal:Research in Experimental Medicine, volume 164, pages 169-173 (issn: 0300-9130, eissn: 1433-8580,

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Authors: A, Engin;

doi: 10.1007/bf01852332

pmid: 4453664

Hyperactivation of fibroplasia by the transferable sulphur in wound healing

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Abstract

Glutathione has important functions in the process leading to cell growth and division. The healing phenomena in the excissional skin lesions of guinea pigs are stimulated by the local treatment of thiourea. Its sulphur was physiologically incorporated in the soluble thiol groups interpreted as glutathione. The statistical average of tissue glutathione values were determined by the DTNB method as 0.666 ± 0.033 mg/g wet, weight after thiourea treatment in test group and 0.241 ± 0.034 mg/g wet weight in control group.

Related Organizations

Hacettepe University
Turkey

Keywords

Wound Healing, Guinea Pigs, Granulation Tissue, Thiourea, Animals, Mitosis, Fibroblasts, Glutathione, Chromatin

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