Influence of erythrocyte deformability on circulation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1973 English Publisher:Springer Science and Business Media LLCJournal:Research in Experimental Medicine, volume 160, pages 89-94 (issn: 0300-9130, eissn: 1433-8580,

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Authors: H, Rogausch;

doi: 10.1007/bf01852246

pmid: 4701642

Influence of erythrocyte deformability on circulation

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Abstract

In an isolated perfused guinea pig liver the influence of low deformable erythrocytes on blood flow has been tested. Down to 30% reduced deformability of red cells resulted in a significant reduction of flow peculiarly at low pressures. Decrease of venous out-flow hematocrit at nearly normal liver weight indicated slowly circulating rigid red cells, signalizing less effectiveness of the Fahraeus-Lindquist-effect.

Related Organizations

Drittes Physikalisches Institut
Germany

Keywords

Perfusion, Erythrocytes, Liver, Microcirculation, Guinea Pigs, Animals, Capillaries, Liver Circulation

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