Regulation of antibody-formation in parabiosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1972 English Publisher:Springer Science and Business Media LLCJournal:Research in Experimental Medicine, volume 157, pages 87-94 (issn: 0300-9130, eissn: 1433-8580,

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Authors: F, Scheiffarth; H W, Baenkler; H H, Thümmel;

doi: 10.1007/bf01851690

pmid: 5064362

Regulation of antibody-formation in parabiosis

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Abstract

This work was designed to show whether antibodies can influence the immune responseafter sensitization. — NMRI-mice were sensitized with sheep red blood cells (SRBC) and joined by parabiosis. After different intervals the immune response was examined by detection of single antibody-forming cells using the plaque-technique. For demonstration of a possible transfer of SRBC or antibodyproducing cells only one parabiont was sensitized.

Related Organizations

University of Erlangen-Nuremberg
Germany
Universitätsklinikum Erlangen
Germany

Keywords

Erythrocytes, Sheep, Time Factors, Parabiosis, Mice, Inbred Strains, Antibodies, Antigen-Antibody Reactions, Mice, Antibody Formation, Immune Tolerance, Animals, Female, Antibody-Producing Cells

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