Two dimensional echocardiography is an excellent method to evaluate anatomic cardiac structures and assess myocardial function. Although the evaluation of myocardial perfusion has been studied extensively experimentally [1, 2] in the last decade, myocardial contrast two-dimensional echocardiography only recently has shown its clinical potential [3, 4, 5, 6, 7]. These studies were performed in the cardiac catheterization laboratory using intracoronary injections or recently, after intravenous injections [3, 8]. This goal has been mainly achieved by Dr. Steven Feinstein of the University of Chicago who created a new method sonication to prepare echocontrast agents containing microbubbles capable of capillary transit.