
doi: 10.1007/bf01788363
pmid: 8825033
Ca2+-uptake into intracellular stores is mediated by the sarco/endoplasmic reticulum Ca2+ATPases (SERCAs). This review deals first with the gene structural and the characterization of the tissue-specific SERCA2 transcript processing. Secondly, the two different protein isoforms and their regulation are described. Finally, this review ends with a discussion on the possible physiological role of the SERCA2 isoform diversity.
Sarcoplasmic Reticulum, Ion Transport, Transcription, Genetic, Calcium-Binding Proteins, Animals, Humans, Calcium-Transporting ATPases, Gene Expression Regulation, Enzymologic, Phospholamban
Sarcoplasmic Reticulum, Ion Transport, Transcription, Genetic, Calcium-Binding Proteins, Animals, Humans, Calcium-Transporting ATPases, Gene Expression Regulation, Enzymologic, Phospholamban
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