Ultrafast (Cine) CT scanning provides cross-sectional millisecond tomography, and therefore combines digital imaging and high resolution without the need for either cardiac catheterization or any form of ECG gating. Fifty millisecond multilevel scanning at rates of 17 scans per second allows quantitation of left ventricular (LV) function at each tomographic level during a cardiac cycle. Calculations of global and regional ejection fraction can be obtained, and in addition ultrafast CT also has the potential for providing unique data concerning regional wall thickening, mass and even regional myocardial perfusion. Interventional studies with exercise and pharmacological agents have commenced and are currently being evaluated.