Hypoprothrombinemia Due to Cefamandole

descriptionPublicationkeyboard_double_arrow_right Article 01 Dec 1988 English Publisher:Springer Science and Business Media LLCJournal:Klinische Wochenschrift, volume 66, pages 1,190-1,192 (issn: 0023-2173, eissn: 1432-1440,

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Authors: V M, Conraads; H E, Demey; L G, Heytens; L L, Bossaert;

doi: 10.1007/bf01727668

pmid: 3062269

Hypoprothrombinemia Due to Cefamandole

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Abstract

Two patients are described with severe coagulation disturbances, in one instance leading to extensive skin bleeding, secondary to the use of cefamandole. This cefalosporin antibiotic carries the same N-methylthiotetrazole side chain as moxalactam. Pathogenetic mechanisms leading to hypoprothrombinemia, its prevention and treatment are discussed.

Related Organizations

Antwerp University Hospital
Belgium
University of Antwerp
Belgium

Keywords

Male, Pneumonia, Middle Aged, Hemorrhagic Disorders, Kidney Transplantation, Amputation, Surgical, Postoperative Complications, Cefamandole, Humans, Female, Hypoprothrombinemias, Diabetic Angiopathies, Aged

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