No evidence of mycoplasmas in peripheral blood mononuclear cell fraction of HIV-infected patients

descriptionPublicationkeyboard_double_arrow_right Article 01 May 1994 Netherlands English Publisher:Springer Science and Business Media LLCJournal:Infection, volume 22, pages 204-206 (issn: 0300-8126, eissn: 1439-0973,

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Authors: Kuppeveld, F.J.M. van; Melchers, W.J.G.; Kissing, J.; Logt, J. van der; Galama, J.M.D.;

doi: 10.1007/bf01716704

pmid: 7927818

handle: https://repository.ubn.ru.nl/handle/2066/76528 , 2066/76528

No evidence of mycoplasmas in peripheral blood mononuclear cell fraction of HIV-infected patients

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Abstract

In this study, the prevalence of mycoplasmas in peripheral blood mononuclear cells (PBMC) from HIV-infected individuals was investigated using a mycoplasma genus-specific PCR assay. No mycoplasmas were detected in the PBMC samples from any of the 25 HIV-infected individuals (CDC 2, n = 8; CDC 3, n = 2; CDC 4, n = 15) or ten HIV-seronegative controls. As an internal control, HIV specific sequences were detected in the samples from all HIV-seropositives. These negative results do not support a suggested role of mycoplasmas as co-factor in the progression of HIV infection towards AIDS.

Country

Netherlands

Related Organizations

Radboud University Nijmegen
Netherlands
Utrecht University
Netherlands

Keywords

DNA, Bacterial, Male, AIDS-Related Opportunistic Infections, Base Sequence, Alle HP's en lijnen, Mononuclear, Molecular Sequence Data, Bacterial, DNA, Polymerase Chain Reaction, Mycoplasma, SDG 3 - Good Health and Well-being, Risk Factors, Case-Control Studies, Leukocytes, Leukocytes, Mononuclear, Prevalence, Humans, Female, Mycoplasma Infections

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