Cefotaxime and desacetyl cefotaxime in human bile

descriptionPublicationkeyboard_double_arrow_right Article 01 Mar 1983 Germany English Publisher:Springer Science and Business Media LLCJournal:Infection, volume 11, pages 118-120 (issn: 0300-8126, eissn: 1439-0973,

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Authors: Kees, Frieder K.; Strehl, E.; Dominiak, P.; Grobecker, H.; Seeger, K.; Seidel, G.; Neuhaus, B.; +1 Authors

doi: 10.1007/bf01641077 , 10.5283/epub.26859

pmid: 6305848

Cefotaxime and desacetyl cefotaxime in human bile

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Abstract

Ten patients were injected with 2 g cefotaxime i. v. The antibacterial activity in the bile was measured by the agar diffusion test and the concentrations of cefotaxime and desacetyl cefotaxime were determined by high performance liquid chromatography. The values found allow the use of cefotaxime in infectious biliary diseases.

Country

Germany

Related Organizations

University of Regensburg
Germany

Keywords

Adult, Male, Immunodiffusion, Bacteria, Bile/metabolism, Cefotaxime, Microbial Sensitivity Tests, Middle Aged, ddc:615, 615 Pharmazie, Bacteria/drug effects, Cefotaxime/pharmacology, Bile, Humans, Biological Assay, Female, Chromatography, High Pressure Liquid, Aged

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