
doi: 10.1007/bf01577206
Supplementation of cultures ofAerobacter aerogenes 62-1, 43/4 h after initiation of growth withd-glucose (20 mM), resulted in a threefold increase in the production of aerobactin. Administration ofl-lysine under similar conditions led to a twofold incrasse in the yield of the siderophore. Studies with a cell-free system ofAerobacter aerogenes 62-1 revealed considerable stimulation of lysine-N6-hydroxylase activity by glucose and several of its derivatives. Inclusion of ferric chloride (0.1 mM) in the growth medium led to the repression of both lysine-N6-hydroxylase and aerobactin synthetase.
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