The SGOT/SGPT ratio?An indicator of alcoholic liver disease

descriptionPublicationkeyboard_double_arrow_right Article 01 Nov 1979 English Publisher:Springer Science and Business Media LLCJournal:Digestive Diseases and Sciences, volume 24, pages 835-838 (issn: 0163-2116, eissn: 1573-2568,

Copyright policy )

Authors: J A, Cohen; M M, Kaplan;

doi: 10.1007/bf01324898

pmid: 520102

The SGOT/SGPT ratio?An indicator of alcoholic liver disease

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Abstract

The SGOT/SGPT ratio is significantly elevated in patients with alcoholic hepatitis and cirrhosis (2.85 +/- 0.2) compared with patients with postnecrotic cirrhosis (1.74 +/- 0.2), chronic hepatitis (1.3 +/- 0.17), obstructive jaundice (0.81 +/- 0.06) and viral hepatitis (0.74 +/- 0.07). An SGOT/SGPT ratio greater than 2 is highly suggestive of alcoholic hepatitis and cirrhosis. It occurs in 70% of these patients compared with 26% of patients with postnecrotic cirrhosis, 8% with chronic hepatitis, 4% with viral hepatitis and none with obstructive jaundice.

Related Organizations

Tufts Medical Center
United States

Keywords

Diagnosis, Differential, Hepatitis, Alcoholic, Liver Cirrhosis, Alcoholic, Liver Diseases, Humans, Alanine Transaminase, Aspartate Aminotransferases, Clinical Enzyme Tests, Hepatitis

13 Research products, page 1 of 2

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